Former BC Iron boss Mike Young will take the reins of Goldfields uranium developer Energy and Minerals Australia.
Mr Young initially joined EMA as chairman last April after leaving the Pilbara iron ore miner he helped found, but will take a more active role as managing director.
He replaces Julian Tapp, who is taking on the chief operating officer role after less than 12 months in the top job.
The well-known former Fortescue Metals Group external affairs boss will focus on managing the approvals process and feasibility assessment for the company's Mulga Rock project, 240km north-east of Kalgoorlie-Boulder,
Mr Young described Mulga Rock as a "world-class uranium deposit" with late 2016 targeted for first production.
He called the leadership change a "natural progression". A new chairman will be named at a later date.
"He will continue to run the project while I focus on the company so really, nothing will have changed except for our business cards," Mr Young said.
The Goldfields is home to WA's most advanced uranium project, with Toro Energy last month putting a $315.6 million price tag on its Wiluna project.
Meanwhile, the Conservation Council of WA says more than 2500 submissions opposing Cameco's proposed Kintyre uranium mine in the Pilbara have been lodged with the State Government's Environmental Protection Authority.
Conservation Council campaigner Mia Pepper said uranium mining - banned in WA until the Barnett Government overturned it in 2008 - poses "unacceptable and unnecessary risks".
"The area that contains the Kintyre uranium deposit is one of the most unique and diverse ecosystems in the country and is directly adjacent to WA's largest national park," Ms Pepper said
The Anti Nuclear Alliance of WA is planning a Valentine's Day stunt outside the EPA's office on St Georges Terrace. It plans to lodge its submission against the Kintyre project along with 2500 paper hearts.
EMA shares last changed hands for three cents.