The broadcaster, who has commentated on Eurovision since 2018, criticised touts for taking tickets away from real fans. Ticket reseller site Viagogo is offering tickets to the final at prices ranging from £2,369-£3,554.
Read more: Eurovision fans fuming as tickets sell out
Rylan tweeted: "To the people selling Eurovision tickets at RIDICULOUS resale prices that aren't proper fans - p*****."
His post also included a gif of a man giving the middle finger.
The former X Factor contestant had earlier shared a more upbeat message as thousands struggled to purchase tickets after Ticketmaster suffered a number of technical problems minutes before they were due to go on sale at midday.
Alongside a picture of him doing promo for Eurovision in 2018, Rylan wrote: "Congrats if you got tickets! If not don’t worry, the Euro Village is gonna be amazing. #Eurovision is gonna take over the whole city. See you soon Liverpool…. All aboard.. (2018 ref for you die hards)."
Fans of the singing contest were outraged on social media as they failed to get tickets for the live events with the grand final selling out in minutes. Ticketmaster was also strewn with errors that kicked customers out of the virtual queue.
A number of notable figures also failed to land tickets including broadcaster Richard Osman who tweeted: “Didn’t get Eurovision tickets. My only hope now is to sing the UK entry.”
Former hockey player and current TV host Sam Quek also wrote: "If it makes anyone feel better… I couldn’t get #Eurovision Grand Final tickets… and I’m presenting the Opening Ceremony! #Ticketmaster."
Specsavers also mocked the ticket problems on Twitter, posting a picture of the error message and a caption that said: "Most common sight right now."
The Eurovision final is set to take place on 13 May at Liverpool's M&S Bank Arena. The event will also be broadcast by the BBC.
Watch below: Eurovision tickets for Liverpool shows to go on sale.