Defibrillators will be mandatory in all public buildings across South Australia including schools, sports facilities and shopping centres, with a founding member of the Wiggles supporting the push.
A private members' bill framed by SA-BEST will also require defibrillators in all emergency service vehicles including police patrol cars, fire trucks and State Emergency Service vehicles.
The bill, introduced in state parliament, includes a maximum $20,000 fine for any organisation that fails to abide by the new provisions.
SA-BEST MP Frank Pangallo said automated external defibrillators sell from about $200, "an extremely small price for government and the private sector to pay to potentially save lives".
"The statistics not only speak for themselves but also paint a very disturbing, deadly picture," he said.
"More than 30,000 people suffer cardiac arrest in Australia each year but only one in 10 survive.
"It's an indisputable fact the availability of a defibrillator dramatically improves a person's chance of survival to 70 per cent."
Yellow Wiggle Greg Page, whose own life was saved when he collapsed in 2020 thanks to bystanders who knew CPR and a nearby defibrillator, has backed the SA-BEST proposals.
"I am proud to support this innovative move towards legislation of Automated External Defibrillators in the community," he said.
"We know that having a complete chain of survival - which includes AEDs - is proven to increase survival rates from sudden cardiac arrest."
Under the SA-BEST legislation, the state's health minister will establish a register of where all defibrillators are located and at what times they are accessible to the public.
The information must also be available through a smartphone app.