The next generation of Australian vaccine workers will be trained out of a new centre in Melbourne's southeast.

The Monash Centre for Advanced mRNA Medicines Manufacturing and Workforce Training in Clayton is receiving a $10 million grant from the Victorian government.

It will train Australia's future mRNA workforce and complement Moderna's nearby mRNA vaccine manufacturing facility, the first of its kind in the southern hemisphere.

Once completed in 2024, the manufacturing site will be capable of producing 100 million vaccine doses a year.

Premier Daniel Andrews said Melbourne was among the great global cities of science, but funding was needed to train more staff to help it thrive.

The new centre is expected to particularly help industry workers in remote areas and overseas.

"This is not just for students that haven't yet graduated or even those that have postgraduate study, it will be for people who work in industry now who work in labs a long way from here and indeed, perhaps overseas," he told reporters on Thursday.

"[They] will come here to learn very specifically and to get the leave with a competency and a clear understanding and skills that they don't have to bolt on and add on to the already considerable resume."

Monash University Deputy Vice-Chancellor Professor Sharon Pickering said a range of courses would be offered.

"We need to develop the greatest curriculum pedagogy whether it be from a short course, all the way through to a credentialed, postgraduate course," she said.

In October, BioNTech also agreed in principle with the state government to develop a clinical-scale mRNA manufacturing facility in Melbourne.