A second man has appeared in court charged with the shooting murder of a Melbourne dressmaker whose body lay undiscovered for 10 days.

Lawrence Michael Duca, 45 of Coburg, is charged with killing The Phuong Vuong at Deer Park on June 16.

He appeared in Melbourne Magistrates' Court on Tuesday night and did not apply for bail.

The court was told Duca has medical issues from a vehicle crash last year, in which revived multiple broken bones and needed his ankle reconstructed.

He was on several pain and anti-depressant medications and it was also Duca's first time in custody, his lawyer said.

Earlier on Tuesday, Abelardo Ramos, 35, made a brief appearance in the same court also charged with Mr Vuong's murder.

Ramos sat through most of the filing hearing with his arms folded.

Mr Vuong, 49, was found dead at his Deer Park home, from which he ran a sewing business, about 4.25pm on June 26.

Police believe he hadn't been seen since June 15.

The two accused men were arrested on Monday.

Duca was remanded in custody to reappear in Melbourne Magistrates' Court on Wednesday for a filing hearing.

Ramos was remanded in custody to appear in court on November 21 for a committal mention.

AAP

Latest From 7News