While China moves closer to containing a fresh outbreak in Beijing, the coronavirus has taken a stronger hold in many countries, particularly the United States.
Surging infections across southern US states have highlighted the risks of reopening economies without effective treatment or vaccines.
Another record daily increase in India has pushed the country's caseload towards half a million, while other countries with large populations like Indonesia, Pakistan and Mexico grappled with large infection numbers and strained healthcare systems.
South Africa, which accounts for about half of the infections on the African continent with 118,375, reported a record 6579 new cases, as transmissions increased after it loosened what had been one of the world's strictest lockdowns earlier this month.
Mexico reported some of its highest 24-hour counts so far, with 6104 new cases and 736 additional deaths, as its treasury secretary began isolating at home after a positive test.
In China, where the pandemic originated in December, authorities have mobilised resources for mass testing and locked down parts of Beijing this month due to an outbreak that has infected 260 people.
The 11 new cases reported in the capital on Friday continued a downward trend that suggests transmissions have been largely brought under control.
The United States, which counts the most infections in the world, is seeing daily jumps in COVID-19 cases nearing the peak reached during late April.
Arizona's 3056 additional infections reported on Thursday marked the fourth day in a week with a increase of more than 3000.
Transmissions have spiked following Republican governor Doug Ducey's decision to lift stay-at-home restrictions in May.
Twenty-three per cent of tests conducted in the state om the past seven days have been positive, nearly triple the national average, and a record 415 patients were on ventilators.
The United States reported 34,500 COVID-19 cases on Wednesday, slightly fewer than the day before, but still near the high of 36,400 reached on April 24, according to Johns Hopkins University.
The daily average has climbed by more than 50 per cent in the past two weeks, an Associated Press analysis found.
India, which has the world's second-largest population, has seen regular record daily increases. The 24-hour spike of 17,296 new infections reported on Friday raised the national caseload past 490,000, including 15,301 fatalities.
Indian Railways delayed the resumption of regular train services by more than a month, until August 12.
In India and in neighbouring Pakistan, government leaders have resisted new restrictions, citing economic concerns.
The world's fourth-most populous country, Indonesia, passed 50,000 cases on Thursday, with at least 2620 deaths, the highest number of cases and fatalities in south-east Asia. That's up from just two positive cases in early March.
The virus' return is also erasing hard-won gains in South Korea, which reported 39 newly confirmed cases on Friday, mostly from the Seoul area.
Australia on Friday reported 37 new cases, including 30 in Victoria state, where health authorities are scrambling to contain an outbreak.
In Europe, the official in charge of Spain's response to COVID-19 said imported infections were a growing source of concern as the continent readies to welcome more visitors.
Epidemiologist Fernando Simon said on Thursday that 54 people who had contracted the disease in the past week had been linked to recently arrived visitors in Spain.
He suggested controls should be strict and regional and local governments should be ready to apply localised isolation to avoid spreading the disease.
In Paris, the Eiffel Tower reopened to visitors after its longest peacetime closure of 104 days.
In Britain, Health Secretary Matt Hancock warned the government had the power to close beaches and other public spaces amid growing concerns over the public's adherence to social distancing rules after huge crowds gathered on English beaches.
There were also concerns surrounding jubilant Liverpool fans gathering outside the soccer club's stadium to celebrate the team's first league title in 30 years.