Anger, frustration and sadness over the decision not to charge Kentucky police officers for Breonna Taylor's death has poured onto America's streets.
Protesters have lashed out at a criminal justice system they say is stacked against black people.
Violence seized the demonstrations in her home city of Louisville as gunfire rang out and wounded two police officers.
Activists, celebrities and everyday Americans have been calling for charges since Taylor, an emergency medical worker, was shot multiple times by white officers who entered her home during a drugs investigation in March.
State attorney general Daniel Cameron, a Republican and Kentucky's first black top prosecutor, said while the officers had a no-knock warrant, the investigation showed they announced themselves before entering.
A grand jury returned three charges of wanton endangerment on Wednesday against fired officer Brett Hankison over shooting into a home next to Taylor's with people inside.
Hundreds of demonstrators chanted Taylor's name and marched in cities including New York, Washington, Philadelphia, Las Vegas and Portland.
People gathered in Millennium Park, Chicago, chanting demands for justice as drivers in Michigan Avenue honked their horns.
Police in Atlanta unleashed chemical agents and made arrests after some protesters tried to climb on a SWAT vehicle.
In Wisconsin, peaceful marchers blocked traffic on an interstate and spoke about Taylor on the steps of the state Capitol.
Nearly 100 people were arrested in Louisville, police said, after what had been peaceful protests.
Police said vehicles were damaged, fires were set in bins and several shops were looted.
Two officers were shot and Interim Police Chief Robert Schroeder said both are expected to recover. One was undergoing surgery.
Schroeder said a suspect is in custody, offering no details about whether that person was participating in the protests.
Along with George Floyd, a black man killed by police in Minneapolis in May, Taylor's name became a rallying cry during nationwide protests that called attention to entrenched racism and demanded police reform.
Her image is painted on streets, emblazoned on protest signs and silk-screened on T-shirts worn by celebrities.
The FBI is still investigating potential law violations in connection with the raid at Taylor's home on March 13.
Ben Crump, a lawyer for Taylor's family, denounced the decision not to charge officers over Taylor's death as "outrageous and offensive".
Cameron said the officers acted in self-defence after Taylor's boyfriend fired at them.
Kenneth Walker told police he heard knocking but did not know who was coming in and fired in self-defence.
The warrant was connected to a suspect who did not live there, and no drugs were found inside. The city has since banned such warrants.
US President Donald Trump read a statement from Mr Cameron saying "justice is not often easy".
He later tweeted he was "praying for the two police officers that were shot".
Democratic presidential candidate Joe Biden and his running mate, Kamala Harris, called for policing reform.
"We must never stop speaking Breonna's name as we work to reform our justice system, including overhauling no-knock warrants," Harris said on Twitter.
The three wanton endangerment charges Hankison faces each carry a sentence of up to five years.
Last week, the city agreed a settlement with Taylor's mother, Tamika Palmer, which includes $US12 million and police reforms.