Police are searching for clues in the mysterious disappearance of a young mother who was abducted from a small town service station in Michigan after completing her late night shift there.

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Investigators are relying on tips to help them piece together what happened during the 15-minute period Jessica Heeringa went missing. File photo

Police are searching for clues in the mysterious disappearance of a young mother who was abducted from a small town service station in Michigan after completing her late night shift there.

Authorities have pinpointed a 15-minute window in which 25-year-old Jessica Heeringa vanished from the Exxon Mobil station at Norton Shores on Friday night.

The station did not have any CCTVinstalled so there is no vision of what happened on the night.

Ms Heeringa made her last sale at 11pm, police said.

At 11.15pm, a concerned customer called police reporting that the petrol station had been left unattended.

Ms Heeringa left behind her car keys and purse. On the counter sat the cleaning supplies she normally used when tidying up at the end of the night.

Investigators are relying on tips to help them piece together what happened during the 15-minute period Ms Heeringa went missing.

It appeared robbery was not a motive as the store's cash drawer was left untouched.

“She was going to get out in 15 minutes,” Jessica's mother told ABC News.

“In 15 minutes that store would've been closed and she would've been on her way home.”

The mother added that someone saw her daughter walk out of the store with a man but when they got to his van, a struggle ensued.

Investigators are searching for a grey minivan seen behind the station shortly before Ms Heeringa went missing.

The driver is described as a white male, about 30-40 years old, wearing a bright red or orange sweatshirt.

The mother said she told her daughter several times that she worried about her working late by herself.

"She said, 'Mum, don't worry. I can handle anybody,'" Shelly Heeringa said.