Six years ago, Jana Kolichis was walking uphill after a concert when she turned to see her friend Kylie Taylor struggling to breathe.
They had known each other since high school but Ms Kolichis had never really understood the full impact of her friend's cystic fibrosis.
"I didn't realise how hard it was for her to do something as simple as walking up a hill and it really shocked me," she said.
"I was just walking normally and Kylie was lagging behind trying to breathe."
Since that day Ms Kolichis, now 28, has helped to raise awareness of the debilitating condition.
She will run the 14km course of this year's HBF Run for a Reason on Sunday to raise money for Cystic Fibrosis WA.
Ms Kolichis has a weekly running program and will also compete in the New York marathon later this year.
That is in stark contrast to Ms Taylor, who needs physiotherapy, antibiotics, vitamins, pancreatic enzymes and an inhaler just so she can breathe and eat.
Ms Taylor was diagnosed with the condition as a child and lost her older brother to cystic fibrosis when he was just 14.
For Ms Taylor, the most frustrating part of having cystic fibrosis is that she will never be completely independent, making family and friends very important to her.
"It isn't something you can really manage completely by yourself and it is kind of inevitable that it gets worse over the years," she said.
WA companies are urged to promote healthy competition in the workplace by registering a team in the annual event.
Among those already signed up is consultancy firm Ajilon. A 50-strong team will don matching vests when they descend on the WACA Ground to complete the 14km and 4km courses.
Team captain Fiona Gardener said it was a great way for the company to gain exposure while supporting a worthy cause.
"It gives you a positive image in the community and is really good in terms of boosting morale and engaging staff," she said.
The HBF Run for Reason aims to raise more than $400,000 for the Heart Foundation WA, Cancer Council WA, Diabetes WA and Lifeline WA.
Corporates, sporting clubs, social clubs and schools with a minimum of four competitors can enter as a team.
For more information visit www.hbfrun.com.au.