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Keira Knightley. Picture: AP

Newlywed Keira Knightley has reportedly replaced Oscar winner Anne Hathaway in director Lynn Shelton's new movie Laggies.

Entertainment Weekly reports the Les Miserables star has dropped out of the comedy project because it clashed with Christopher Nolan's Interstellar.

Knightley has stepped in and will play a woman struggling with a marriage proposal in the film, which will co-star Chloe Moretz and Sam Rockwell.

Knightley married musician James Righton on Saturday.