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Northwest Queensland grazier John Lethbridge's family has been torn apart because they couldn't hold out for rain any longer.

And at aged 61, having sold off more than 90 per cent of his cattle for next-to-nothing, he's facing possible bankruptcy.

"I've been on the land for 61 years and in that time I've experienced fire, flood and numerous droughts," he told AAP.

"A flood or fire is like getting injured, where as this drought is more like facing cancer."

More than 70 per cent of the state has been drought declared and Mr Leftbridge's 110,000 acre farm between Richmond and Hughenden hasn't had any decent rain since 2012.

He was forced to sell off all but 600 of his 6000 cattle last year.

Mr Lethbridge says it was a tough decision to make, but nothing compared to the heartache he felt earlier this month when he said goodbye to his daughter and her family.

His 34-year-old daughter and son-in-law had worked alongside him on the cattle station for many years.

Recently they were forced to head to the Sunshine Coast with their two young children in search of work as there was no money left in the farm account to pay them.

"It was a real turning point," Mr Lethbridge said.

"Basically we've had to re-evaluate all our plans, all our hopes and aspirations and dreams going forward because there's no certainty."

Normally an optimist, Mr Lethbridge can't see any relief in sight.

Last weekend 20mm of rain fell on his dry, cracked fields but it wasn't nearly enough to break the drought - which he says is the worst to hit the state in more than 100 years.

He's kept 600 cows and calves on hand so he can restart his once bustling cattle station if significant rain comes this wet season.

But if there's no rain he may have to consider walking away from his livelihood or giving away his cattle and finding temporary work elsewhere.

"You've got to do what you've got to do," he said.

"But at 61 I was hoping we'd be able to kick back a little bit."