The State's horror run on the road has continued today when a man died after the car he was driving hit a tree in Mundaring.
It is the fifth road fatality this week, after a double fatality in Kellerberin, a woman and her unborn baby died on Brookton Highway and a cement truck driver was killed in a crash with a truck.
The crash happened at about 9am on Mundaring Weir Road near McCallum Road in Mundaring.
The driver died at the scene.
Major Crash Investigators and local police are at the scene.
A road block is in place on Mundaring Weir Road near Phillips road.
Motorists are advised to avoid the area.
Police Commissioner Karl O'Callaghan admitted he was at a loss to come up with a new message to promote road safety.
“Some of these things are inexplicable, and that is very difficult to target strategies towards,” Mr O'Callaghan said.
“So sometimes you are left thinking what do you do next, and can we go any further with this.”
Meanwhile, a man has been airlifted to Royal Perth Hospital after he was thrown from his vehicle in West Pinjarra car roll-over.
The RAC Rescue helicopter was sent to the scene at Forrest Highway, near the intersection of Greenlands Road, about 10.45am.
The man suffered facial injuries.