Theroux and his company Mindhouse Productions will be producing the four-part docu-series Follow the Leader, where Maddix will explore communities existing on the fringes of society.
Airing on Dave and UKTV Play, Follow the Leader will look at the way the COVID-19 pandemic and conspiracy theories have emboldened these groups to splinter off from society.
The series will cover fringe political movements, radicals and other ostracised sects as Jamali spends time with their leaders to find out the roots of their devotion.
"I've always been fascinated by cults and sub-cultures – people that choose to live as 'other'. Comedians are typically outsiders and I've made a career from observing people's behaviour and nuances from this perspective," he said.
"With this show I want to explore the more extreme worlds people choose to live in and discover who they are and crucially WHY they do what they do."
Theroux also expressed excitement to be part of the behind-the-scenes team of Follow the Leader, since it follows some of the same themes of his own documentaries.
"In times of great weirdness, it gives me some consolation to know that we have intrepid connoisseurs of the dark, the troubling, the downright baffling of the calibre of Jamali," the filmmaker said.
"He is the real deal: brave funny, curious – someone who can walk the fine line of challenging and confronting where necessary but also being empathetic and kind. I'm proud to be with him on the Follow the Leader journey, wherever it may take us."
Jamali Maddix will be a familiar face to many viewers from competing in the 11th series of Taskmaster, and for his prior documentary Hate Thy Neighbor on political extremism.
Follow the Leader with Jamali Maddix will premiere later this year on Dave and UKTV Play.
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