Victorian MPs will look at whether the state's contact tracing system is up to withstanding future COVID-19 outbreaks.
Chief Health Officer Brett Sutton is expected to give evidence at the upper house inquiry.
Its chair and Reason Party MP Fiona Patten says she wants the hearings to "provide the confidence and assurance that we have an excellent contact tracing and testing regime".
Ms Patten said the inquiry would aim to "protect us for when we hit the inevitable third wave, so we won't see anything like the lockdowns and deaths that we have seen this year.
"We know we've made mistakes but we also know that we have learned a lot in that time," she told AAP on Friday.
Victoria's head of testing Jeroen Weimar and Australia's chief scientist Alan Finkel are among the public servants and experts set to be called before the Legal and Social Issues Committee.
"I will want them to assure us and to show us how our system works and how our system will be able to respond when we do get further outbreaks," Ms Patten said.
"It would be naive to think that we're not going to."
Her comments come as Victoria records its seventh day in a row of no new cases or deaths.
Ms Patten said she expected at least two full days of public hearings from November 16 and to examine outbreaks from the Cedar Meats abattoir and Islamic schools in suburban Melbourne.
The inquiry is due to provide a final report to parliament by December 14.
It's separate from a judicial probe by retired judge Jennifer Coate into Victoria's botched hotel quarantine system.
Her interim report released on Friday recommends an overhaul of the system.
Under the proposals, returned overseas travellers would be assessed to see if they are suitable for home quarantine.
Those unable to quarantine at home would go to hotels, with police on site 24/7.
Victoria's second COVID-19 wave, which led to more than 18,000 new infections and 800 deaths, began with staff outbreaks at the Rydges and Stamford Plaza quarantine hotels.