Panama has lifted a five-month-old coronavirus measure that had restricted women from going out one day and men the next.
The rules limiting when people could go out for essentials proved controversial because it led to harassment of transgender people.
Health Minister Luis Antonio Sucre urged caution despite the lifting of the rule, which had been in place since March.
"Today we are beginning a new stage," Sucre said, "in which men and women can go out when they wish. We have to be very careful, we have to remember that the pandemic is not over."
Panama has had 101,745 reported coronavirus cases and 2166 deaths.
Similar measures were also tried in Peru to reduce the number of people on the street and slow the spread of contagion.