Patrick Mahomes won the battle of the elite quarterbacks, passing for four touchdowns as the Kansas City Chiefs defeated the Baltimore Ravens in a marquee matchup between two of the league's top franchises.
Mahomes completed 31 of 42 passes for 385 yards and also rushed for a touchdown as the Chiefs improved to 3-0 on the season and showed why they are the favorites to repeat as Super Bowl champions.
Quarterback Lamar Jackson completed 15 of 28 passes for a just 97 yards and one touchdown in the loss for Baltimore, who had their 14-game regular season win streak snapped.
Jackson's 97 yards was his lowest total in more than two dozen games as a starter in the NFL.
Jackson also had 83 rushing yards on nine carries for the Ravens, who looked nothing like the team that averaged 35.5 points in winning their first two games.
Mahomes, on the other hand, used all his receiving weapons Monday, making sure five players earned more than 60 catching yards for the Chiefs, who are 3-0 to begin the season for the fourth straight year.
Travis Kelce led Kansas City with 87 receiving yards on a half dozen catches.
Even left tackle Eric Fisher and fullback Anthony Sherman caught touchdown passes, as did receivers Tyreek Hill and Mecole Hardman. Chris Jones had four sacks and also two forced fumbles.
Also topping 60 yards were Hardman (81), Hill (77), Clyde Edwards-Helaire (70) and Sammy Watkins (62).
The Chiefs had 517 yards and converted 10 of 13 third-down opportunities.
"The good thing about playing a team firing on all cylinders is they can show you where you are weak at," said Ravens defensive end Calais Campbell. "I am confident we are going to rebound. We want to earn the right to see them again."
The Ravens finished with just 228 yards of total offence.
Mahomes passed for three touchdowns and ran for another as the Chiefs held a 27-10 halftime lead.