Jurgen Klopp's side battled to a hard-fought 4-3 victory over Leeds in their opener, before dispatching Frank Lampard's Chelsea in emphatic style.
Arsenal's improvement under Mikel Arteta continues to show with wins over Fulham and West Ham, alongside an impressive 2-0 Carabao Cup victory at Leicester.
It is the north London club who enter ahead in the table by virtue of goal difference and they have a chance to lay down an early marker.
Date, time and venue
Liverpool vs Arsenal is scheduled for an 8pm BST kick-off on Monday, September 28.
This match will be played behind closed doors at Anfield with no fans due to be present due to government guidelines regarding coronavirus.
How to watch
TV channel: The match will be shown live on Sky Sports' Premier League and Main Event channels, and is available via Now TV
Jurgen Klopp will be without Jordan Henderson for Monday's clash after the midfielder was forced off at half-time of the Reds’ win at Chelsea last weekend after feeling tightness in his thigh.
Thiago Alcantara made his bow from the bench as a result, but he could be in line for his full debut against Arsenal.
Liverpool will also be without Joel Matip, who is suffering with a hamstring injury, but both Joe Gomez and Billy Koumetio are available having returned to training on Friday.
Arsenal are set to welcome Kieran Tierney and David Luiz back into the side after their respective injuries.
Saed Kolasinac will therefore likely be replaced, with Tierney likely to operate at left-wing back with Luiz at the heart of defence.
The pair's return is a welcome boost for Mikel Arteta, who will be without Sokratis Papastathopoulos, Cedric Soares, Shkodran Mustafi, Gabriel Martinelli, Calum Chambers and Pablo Mari.
Liverpool predicted XI: Alisson, Alexander-Arnold, Fabinho, Van Dijk, Robertson, Thiago, Keita, Wijnaldum, Salah, Mane, Firmino.
Arsenal predicted lineup: Leno; Luiz, Gabriel, Kolasinac; Bellerin, Ceballos, Xhaka, Saka; Willian, Aubameyang, Lacazette
Prediction: Liverpool 2-1 Arsenal
Though Arsenal will enter the game full of confidence after a quick start to the season, it's difficult to look past Liverpool for the home win.
Liverpool proved pragmatic in a routine win over Chelsea last time out, with new signing Thiago slotting in immediately to claim a new Premier League record for the most passes completed in a single 45-minute showing.
Of course, Arsenal have beaten both Chelsea and Liverpool to claim back-to-back trophies but this is their first real test of their league campaign, and I'm expecting the home side to come out on top.
Head to head (h2h) history and results
Liverpool and Arsenal are certainly no strangers having met 230 times in their history.
It's the home side who enter the fixture with the marginally better record, having won on 89 occasions, as opposed to Arsenal's 80 wins, alongside 61 draws.
Arsenal have beaten Liverpool twice on the bounce, however, most recently in the Community Shield, where Mikel Arteta's side won on penalties.
Betting odds and tips
- Liverpool to win: 8/15
- Arsenal to win: 6/1
- Draw: 4/1
- Liverpool to win 2-0: 9/1
- Mo Salah to score: 10/11
Odds courtesy of Betfair Exchange. Click here to find out more.
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