President Bashar al-Assad says the United States should learn the lesson of Iraq and withdraw from Syria, and promised to recover areas of the country held by US-backed militias through negotiations or force.
In an interview with Russia Today, Assad said the government had "started now opening doors for negotiations" with the Syrian Democratic Forces (SDF), a Kurdish dominated militia alliance that controls parts of northern and eastern Syria where US forces are stationed.
"This is the first option. If not, we're going to resort to ... liberating those areas by force. We don't have any other options, with the Americans or without the Americans," he said. "The Americans should leave, somehow they're going to leave".
"They came to Iraq with no legal basis, and look what happened to them. They have to learn the lesson. Iraq is no exception, and Syria is no exception. People will not accept foreigners in this region anymore," he said.
Responding to US President Donald Trump's description of him as "Animal Assad", the Syrian leader said: "What you say is what you are". Trump called Assad an animal after a suspected poison gas attack on a rebel-held town near Damascus in April.
Assad reiterated the government's denial that it carried out the attack in the eastern Ghouta town of Douma, saying that the government did not have chemical weapons and it would not have been in its interest to carry out such a strike.
The Douma attack triggered missile strikes on Syria by the United States, Britain and France which they said targeted Assad's chemical weapons program.
Assad has recovered swathes of Syrian territory with military backing from Russia and Iran and is now militarily unassailable in the conflict that began in 2011.