Australia's AstraZeneca vaccine rollout is set to face further scrutiny after four people in Queensland experienced allergic reactions to their first doses.
Health authorities have urged people with a history of anaphylaxis to avoid getting the Covid-19 vaccine until they "get to the bottom of this".
Queensland Health director-general John Wakefield said reactions were not abnormal however the four cases occurred in just 48 hours, prompting concern.
It comes after 10 European countries suspended the rollout of the AstraZeneca vaccine following complications that led to blood clots in recipients.
However like her federal counterpart Greg Hunt, Queensland Health Minister Yvette D'Ath insisted the vaccine was safe for the majority of Queenslanders.
"We are not surprised we're seeing allergic reactions but we do want to let the public know," she said.
She noted the vaccine has always had clear warnings for people allergic to any ingredients of the doses.
Pregnant or breast-feeding women are warned to avoid the vaccines, Ms D'Ath said.
It's not the first issue to hit the vaccine rollout in Queensland after two elderly people were given vaccine overdoses in February.
Restrictions to ease after zero-case streak continues
Brisbane's hospital, aged care facilities and disability providers are also set to come out lockdown on Friday after the state recorded no new cases of community virus transmission.
The lockdown began when a doctor tested positive on Friday after working at Princess Alexandra Hospital and visiting four venues in the city's south on Thursday.
The woman was infected by a patient who also infected a person staying in a separate room at Brisbane's Hotel Grand Chancellor quarantine facility.
Ms D'ath said about 330 of 428 close contacts of the doctor have tested negative for the virus, while no other cases have been reported among PA hospital staff or hotel workers and guests.
The minister said the lack of new community transmission after almost seven days meant the lockdown could end on Friday.
"We are in a very good position going forward over the next couple of days that will hopefully see us be able to lift those restrictions," she said.
Queensland reported six new cases of coronavirus on Wednesday, all from overseas and already in hotel quarantine.
Do you have a story tip? Email: email@example.com