Three men and a woman are accused of involvement in a "dial-a-dealer" Sydney drug syndicate following a series of police raids.
Officers targeting the alleged network since January stopped and arrested two men in a Toyota Hilux at a service station at Merrylands West on Friday afternoon.
Shortly after, a 28-year-old man was arrested during another traffic stop on the Hume Highway at Bankstown, with police allegedly locating cocaine and cash in a search.
A 37-year-old woman was then taken into custody at Greenacre.
Officers also executed search warrants at homes in Croydon, Yagoona, Punchbowl and Arncliffe, seizing more than $80,000 cash, 300 plastic bags of cocaine with an estimated street value of $90,000, 336g of cannabis, two vehicles and electronic devices.
A 31-year-old Liverpool man has been charged with supplying a commercial quantity of prohibited drugs and knowingly directing a criminal group.
The 28-year-old, from Hassall Grove, is accused of supplying prohibited drugs and recklessly dealing with criminal proceeds.
The Arncliffe woman has been charged with supplying a commercial quantity of prohibited drugs and participating in a criminal group.
The three were to appear in Parramatta Bail Court on Saturday.
A 43-year-old Yagoona man also faces two counts of recklessly dealing with the proceeds of crime and has been granted bail to appear in Fairfield Local Court next month.