Eight deaths in just over 24 hours on Victorian roads have left authorities warning drivers that life is too fragile to be complacent behind the wheel.
Assistant Commissioner Doug Fryer told reporters on Sunday he'd never seen anything like these numbers since he took the job, urging motorists to slow down and focus on driving,
"It should never have happened and what it highlights to me is the fragility of life. At the blink of an eye, with one mistake, lives can be taken away," he said at a road safety event in Melbourne.
"You've got people driving round in two tonnes of steel, coupled with speed, coupled with complacency (this) is why all these crashes have happened," he said.
Roads Minister Luke Donnellan said 10 people died on the roads in April - the lowest death toll since data collection - but the weekend "smashed those figures out of the water".
"We need to work together with road safety. We need to take individual responsibility, we need to drive to the conditions," he said on Sunday.
Four women, aged 64 to 75, died on their way home from linedancing on Saturday evening when the car was T-boned at an intersection at Navarre.
A man, who lost control of a car and went through a fence in Heathcote Junction, died just before 2.30am on Sunday while his four passengers escaped unhurt.
Another man died after his car left the road and hit a tree at Bright on the Great Alpine Road about 10.35pm on Saturday, while a 58-year-old man died after his motorcycle collided with a bus.
A female passenger was killed when the car she was in crashed into an embankment at Dixons Creek.