Gunners boss Mikel Arteta has rotated his team for the match ahead of Monday’s Premier League trip to Liverpool – though Runarsson and Saliba are listed among the substitutes.
Goalkeeper Runarsson joined Arsenal on Monday from Dijon and has been training with the squad, while Saliba is slowly being integrated into first-team action given he is still just 19 years old.
Joe Willock gets a start in central midfield, while Eddie Nketiah leads the line after coming off the bench to score the winner against West Ham on Saturday.
Out wide, Reiss Nelson is involved for the first time this season and Nicolas Pepe features too as he looks to get some more minutes under his belt.
Leicester XI: Ward, Amartey, Morgan, Fuchs, Albrighton, Choudhury, Dewsbury-Hall, Gray, Maddison, Thomas, Iheanacho
Subs: Jakupovic, Knight, Justin, Tielemans, Praet, Barnes, Perez
Arsenal XI: Leno, Holding, Luiz, Kolasinac, Maitland-Niles, Elneny, Willock, Saka, Pepe, Nelson, Nketiah
Subs: Runarsson, Bellerin, Saliba, Ceballos, Xhaka, Willian, Lacazette