The Gunners had a hard-fought victory against Rapid Vienna last week, whilst Dundalk lost 2-1 to Molde who scored twice in a ten-minute spell in the second half.
Mikel Artetaâs side were beaten 1-0 by Leicester in the Premier League on Sunday and will be keen to bounce back with a comfortable win against Dundalk.
Hereâs everything you need to know ahead of the match.
When is the match?
The game kicks off at 8pm on Thursday 29 October.
Where can I watch it?
The match will be shown live on BT Sport 2. Subscribers can also stream the match via the BT Sport website or app.
What is the team news?
Runar Alex Runarsson could be making his Arsenal debut in goal on Thursday night. With David Luiz out injured, Shkodran Mustafi should be returning for his first start of the season. Cedric Soares, Mohamed Elneny, Reiss Nelson and Joe Willock are all in contention to make outings on the starting line-up.
As Dundalk have suffered two defeats in their matches against Molde and Waterford last week, Filippo Giovagnoli will have to get his squad in shape ahead of the trip against the 2019 runners-up.
Predicted line ups
Arsenal: Runarsson, Soares, Mustafi, Gabriel, Kolasinac, Elneny, Ceballos, Nelson, Willock, Pepe, Nketiah.
Dundalk: Rogers, Gannon, Cleary, Boyle, Dummigan, Mountney, Murray, Shields, Sloggett, Duggy, Hoban.
This weekend get a Â£10 free bet with Betfair, when you bet Â£10 on a Same Game Multi on the Premier League. Terms: Min Â£10 Same Game Multi bet on any EPL match this Fri - Sun. Free bet valid for 72 hours, awarded at bet settlement. Excludes cashed out bets. T&Cs apply.