According to Deadline, the series will be based on Liz Moore’s bestselling 2020 crime novel of the same name.
The plot follows police officer Mickey (Seyfried) who patrols a Philadelphia neighbourhood that has been hit hard by the opioid crisis. However, when a series of local murders begins, Mickey discovers that her personal history might tie into the case.
Moore and co-showrunner Nikki Toscano said in a joint statement: "We are thrilled that Amanda Seyfried will lead this series about how those initially perceived as victims can band together to regain their power.
“Moore’s family history and her work with harm-reduction and community-service organizations in Philadelphia informed the series, which aims to portray with compassion the lives of those struggling with addiction and the family members who love them.”
The series has not started filming and has no release date yet.
Seyfried recently starred as former entrepreneur Elizabeth Holmes in The Dropout – a 2022 Hulu series that charted the events that led to Holmes being convicted for fraud in 2023.
The actor also recently opened up about the possibility of a third Mamma Mia! film.
However, writer-director Ol Parker has previously reiterated that producer Judy Craymer "always plans for it to be a trilogy" – and Craymer herself said at the end of 2023 that it "will happen".
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