Having opened more than 12 years ago, the Collins Street Surgery will be closing at the end of January.
Practice principal and GP Philip Reid, who has lived in Kalgoorlie-Boulder for more than 32 years, owns the surgery with his wife Pippa, the practice manager.
Two doctors from the surgery will be moving on to other Kalgoorlie-Boulder medical centres, while Dr Reid will be taking long service leave.
He said it was partly for financial reasons as well as for family reasons they had made the difficult decision to close the surgery.
“We wanted to close later in the year, but we didn’t attract enough doctors as I hoped we would in 2013,” Dr Reid said.“It was a hard call to close in January and not in June.”