A temporary bus station will be in place from January 12 so that work on the new underground Perth Busport can begin.
The new station will be on the Roe Street side of the Perth City Link site and will run 75 per cent of the bus services currently running at Wellington Street Bus Station.
Transperth spokesman David Hynes said that the temporary bus station would be in used for about two and a half years while the Wellington Street station is demolished and he new busport is built in its place.
Flyers are being handed out by Transperth today as part of an awareness campaign to make passengers aware of all of the changes.
"What we are doing now is going out to the general community and making sure they have a map and an idea about where they should go to catch their bus on January 12," Mr Hynes said.
"It's really important that passengers make sure they are across the changes in bus arrival and departure points over the next few months.
"A lot of work has gone into making sure the temporary bus station is as comfortable for passengers as possible - it will be monitored by CCTV and there will be shelter for passengers."
The remaining 25 per cent, including routes 31, 213, 881 and 940, will be stopping at the Esplanade Busport from January 5 until a second temporary busport is built on Wellington Street.