Police have appealed for public help to find a woman who has been missing from her home in Melbourne's northwest for two weeks.

Gladstone Park woman Enkeleda Hoxha was last seen in nearby Broadmeadows on Monday, October 26, and has not contacted her family since a brief conversation that day with her husband, police said.

She has not accessed her bank account and police believe she has not left Australia.

Ms Hoxha is described as southern European and about 160cm tall with a medium build, blonde hair and brown eyes.